Andrew J Copp Selected Research

Glycine Dehydrogenase (Decarboxylating)

1/2021	Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System.
11/2020	Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non-ketotic hyperglycinemia.
1/2020	Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase-deficient mice.
3/2015	Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice.

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Andrew J Copp Research Topics

Disease

32	Neural Tube Defects (Exencephaly) 01/2022 - 02/2002
8	Spinal Dysraphism (Spina Bifida) 01/2021 - 09/2002
4	Nonketotic Hyperglycinemia 01/2021 - 03/2015
3	Congenital Abnormalities (Deformity) 11/2020 - 09/2002
2	Hydrocephalus (Hydrocephaly) 01/2020 - 03/2015
2	Fistula 01/2003 - 02/2002
1	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 09/2021
1	Gestational Diabetes (Gestational Diabetes Mellitus) 09/2021
1	Epilepsy (Aura) 11/2020
1	Pathologic Constriction (Stenosis) 01/2020
1	Encephalocele (Encephalocele, Frontal) 11/2019
1	Hyperglycemia 01/2017
1	Diabetes Mellitus 01/2015
1	Obesity 01/2015
1	Genetic Predisposition to Disease (Genetic Predisposition) 08/2013
1	Anencephaly (Aprosencephaly) 01/2012
1	Holoprosencephaly (Arhinencephaly) 08/2010
1	Meckel syndrome type 1 01/2007
1	Dyslexia (Alexia) 05/2006
1	Bardet-Biedl Syndrome (Syndrome, Bardet-Biedl) 10/2005
1	Ischemia 09/2003
1	Blister (Bulla) 02/2003
1	Craniosynostoses (Craniosynostosis) 06/2002

Drug/Important Bio-Agent (IBA)

21	Folic Acid (Vitamin M)FDA LinkGeneric 01/2020 - 02/2002
6	Inositol (Myoinositol)IBA 01/2021 - 09/2002
4	Glycine Dehydrogenase (Decarboxylating)IBA 01/2021 - 03/2015
4	CarbonIBA 11/2017 - 05/2006
3	glycine cleavage systemIBA 11/2020 - 04/2012
3	Glycine (Aminoacetic Acid)FDA LinkGeneric 11/2020 - 03/2015
2	formic acid (formate)IBA 01/2020 - 07/2016
2	Anticonvulsants (Antiepileptic Drugs)IBA 01/2018 - 01/2015
2	NucleotidesIBA 07/2016 - 09/2013
2	Proteins (Proteins, Gene)FDA Link 01/2007 - 10/2005
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2003 - 02/2002
1	GlycosaminoglycansIBA 01/2022
1	Insulin (Novolin)FDA Link 09/2021
1	Aminomethyltransferase (Glycine Synthase)IBA 01/2021
1	IntegrinsIBA 10/2020
1	Monomeric GTP-Binding ProteinsIBA 11/2019
1	Valproic Acid (Depakote)FDA LinkGeneric 01/2018
1	purineIBA 09/2013
1	pyrimidineIBA 09/2013
1	ChloratesIBA 07/2013
1	Heparitin Sulfate (Heparan Sulfate)IBA 07/2013
1	Biomarkers (Surrogate Marker)IBA 08/2012
1	MicroRNAs (MicroRNA)IBA 08/2012
1	Lamin Type B (Lamin B)IBA 01/2012
1	LigandsIBA 08/2010
1	EphA7 ReceptorIBA 01/2009
1	GPI-Linked ProteinsIBA 01/2009
1	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 01/2009
1	Transcription Factors (Transcription Factor)IBA 11/2007
1	rho-Associated KinasesIBA 02/2007
1	CycloleucineIBA 07/2006
1	EthionineIBA 07/2006
1	Biological ProductsIBA 05/2006
1	Methionine (L-Methionine)FDA Link 05/2006
1	Protein Kinase CIBA 01/2004
1	Protein Isoforms (Isoforms)IBA 01/2004
1	HomocysteineIBA 02/2003
1	homocysteine thiolactoneIBA 02/2003
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 06/2002

Therapy/Procedure

2	Therapeutics 01/2015 - 10/2003
1	Traction 09/2003